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Everything you need to know about DMT

DMT — or N, N-dimethyltryptamine in medical talk — is a hallucinogenic tryptamine drug. Sometimes referred to as Dimitri, this drug produces effects similar to those of psychedelics, like LSD and magic mushrooms.

Other names for it include:

  • fantasia
  • businessman’s trip
  • businessman’s special
  • 45-minute psychosis
  • spiritual molecule

DMT is a Schedule I controlled substance in the United States, which means it’s illegal to make, buy, possess, or distribute it. Some cities have recently decriminalized it, but it’s still illegal under state and federal law.

Healthline does not endorse the use of any illegal substances, and we recognize abstaining from them is always the safest approach. However, we believe in providing accessible and accurate information to reduce the harm that can occur when using.

Where does it come from?

DMT naturally occurs in many plant species, which have been used in religious ceremonies in some South American countries for centuries.

It can also be made in a laboratory.

Is it the same thing as ayahuasca?

Kind of. DMT is the main active ingredient ayahuasca.

Ayahuasca is traditionally prepared using two plants called Banisteriopsis caapi and Psychotria viridis. The latter contains DMT while the former contains MAOIs, which prevent certain enzymes in your body from breaking down DMT.